Abstract

Tissue sections of normal mouse lymphoid organs were shown to adsorb erythrocytes of sheep and chicken origin. Only the marginal zone of spleen follicles and the subcapsular and medullary sinuses of lymph nodes were re‐active. Sheep and chicken erythrocytes adhered to the same areas and formed mixed clusters when tested together. Haemadsorption by tissue sections was inhibited by anti‐lymphocyte serum and anti‐mouse IgM. It was also abolished by acid or heat elution. Haemadsorption was probably due to cytophilic antibodies of the IgM class adsorbed to tissue macrophages.

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