Habitual Physical Activity and Sleep in Adults with End-Stage Renal Disease

Abstract

ABSTRACT Background Treatment of end-stage renal disease (ESRD) is necessary to maintain life. However, it can cause physiological, psychosocial, and cognitive impairments, which may impact physical activity (PA) and sleep, although there is insufficient device-based data to elucidate such impacts. Methods PA, sedentary time (SED), and sleep were measured over 7 consecutive days in 12 adults with ESRD (9 dialyzing at home, 3 dialyzing in center) using wrist-worn accelerometers. Validated raw acceleration thresholds were used to quantify time spent in each PA intensity domain and SED, and sleep duration and efficiency. Results Adults with ESRD engaged in little moderate-to-vigorous PA (MVPA; 6.9 ± 9.7 min·d−1) and spent 770.0 ± 68.6 min·d−1 SED. People dialyzing at home engaged in more light-intensity PA than those attending in center (131.2 ± 28.1 versus 106.9 ± 5.4 min·d−1, respectively; P = 0.05); however, neither group met the recommended guidelines for daily MVPA. Individuals with ESRD slept for an average of 286.8 ± 79.3 min·night−1 with an efficiency of 68.4 ± 18.5%, although people dialyzing at home slept for longer and more efficiently (74.5% versus 50.0%, P = 0.07) than those attending in center. Conclusion In this study, we suggest that adults with ESRD engage in less total PA than recommended guidelines and are characterized by poor sleep duration and efficiency. Moreover, results indicate that dialysis mode may influence PA, SED, and sleep, with those dialyzing at home engaging in greater leisure time PA and achieving a greater sleep duration and efficiency.