Abstract

There is growing evidence that caffeine and coffee ingestion prior to exercise provide similar ergogenic benefits. However, there has been a long-standing paradigm that habitual caffeine intake may influence the ergogenicity of caffeine supplementation. The aim of the present study was to investigate the effect of habitual caffeine intake on 5-km cycling time-trial performance following the ingestion of caffeinated coffee. Following institutional ethical approval, in a double-blind, randomized, crossover, placebo-controlled design, 46 recreationally active participants (27 men and 19 women) completed a 5-km cycling time trial on a cycle ergometer 60m in following the ingestion of 0.09g/kg coffee providing 3mg/kg of caffeine, or a placebo. Habitual caffeine consumption was assessed using a caffeine consumption questionnaire with low habitual caffeine consumption defined as <3 and ≥6mg · kg-1 · day-1 defined as high. An analysis of covariance using habitual caffeine intake as a covariant was performed to establish if habitual caffeine consumption had an impact on the ergogenic effect of coffee ingestion. Sixteen participants were classified as high-caffeine users and 30 as low. Ingesting caffeinated coffee improved 5-km cycling time-trial performance by 8 ± 12s; 95% confidence interval (CI) [5, 13]; p < .001; d = 0.30, with low, 9±14s; 95% CI [3, 14]; p = .002; d = 0.18, and high, 8 ± 10s; 95% CI [-1, 17]; p = .008; d = 0.06, users improving by a similar magnitude, 95% CI [-12, 12]; p = .946; d = 0.08. In conclusion, habitual caffeine consumption did not affect the ergogenicity of coffee ingestion prior to a 5-km cycling time trial.

Highlights

  • Caffeine (1,3,7-trimethylxanthine) is consumed daily by approximately 80% of the world’s population (Ogawa & Ueki, 2007)

  • There has been a long-standing paradigm that habitual caffeine intake may influence the ergogenicity of caffeine supplementation (Sökmen et al, 2008), and coffee ingestion

  • Analysis of covariance revealed no influence of habitual caffeine intake on exercise performance, F(1, 43) = 0.013; p = .910; η2p =

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Summary

Introduction

Caffeine (1,3,7-trimethylxanthine) is consumed daily by approximately 80% of the world’s population (Ogawa & Ueki, 2007). Svenningsson et al (1999) reported caffeine-tolerant rats had downregulated levels of adenosine A2A receptors and the corresponding mRNA in rostral parts of striatum, potentially affecting caffeine metabolism, and altering the ergogenic effect of coffee. Habituation is commonly identified as a factor influencing the ergogenic effect of caffeine (Sökmen et al, 2008), research provides conflicting findings (Pickering & Kiely, 2019), and with few studies reporting blood or salivary caffeine concentrations, or assessing men and women. Beaumont et al (2017) demonstrated that the ergogenic effect of caffeine to be reduced after 28 days of caffeine ingestion (Days 1–7: 1.5 mg/kg; Days 8–28: 3 mg/kg), suggesting the development of caffeine tolerance These findings provide equivocal evidence for the existence of a reduction in caffeine’s ergogenicity with continuous ingestion. The aim of the present study was to investigate the effect of habitual caffeine

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