Abstract
A simple, efficient and ecofriendly one-pot synthesis protocol has been developed for the synthesis of 4- arylidene-2-phenyl-5(4)-oxazolones (azlactones) by using an efficient and recyclable solid acid silica-supported H6P2W18O62.24H2O catalyst from a condensation of aldehydes, hippuric acid and acetic anhydride in toluene. The reaction using 0.4WDSiO2 catalyst was carried out under mild conditions with very high yields of up to 89%-93%. The heterogeneous reaction conditions provided a very simple, environmentally friendly, clean, economical and selective protocol for the preparation of these compounds. The catalyst is easily recycled and reused without loss of the catalytic activity. Keywords: Heterogeneous catalysis, Wells-Dawson heteropolyacid, Green Chemistry, 4-arylidene-2-phenyl-5(4)-oxazolones, Azlactones, chemistry, homogeneous, heteropolyacids, organic chemists, bioactive compounds, biological sciences, pharmaceutical science, asymmetric synthesis, amino acids
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
