Abstract
1. 1. Large tetramer fractions were formed when ADP-ribose was added to H4-isozymc of lactate dehydrogenase. 2. 2. In the presence of ADP-ribose, not only the increase in tetramers was observed but also the existence of octamers and aggregates. 3. 3.The dimer fraction decreased markedly. 4. 4. Two pathways in the formation of aggregates were suggested; one starting from monomers and the other from octamers.
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