Abstract
A radiographic skeletal survey was carried out on 20 cases of h˦moglobin SC disease. Slight but significant changes in bone texture of the skull and long bones were noted in about one-third of the patients. These were not related to age or degree of an˦mia. In h˦moglobin SC disease bone infection is very frequent. Avascular joint changes were noted in one-third of the cases, the hips and shoulders being most frequently involved. The avascular process is multifocal, discrete, and subchondral.
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