Abstract
<i>gyrA</i>Mutations in Fluoroquinolone-resistant<i>Clostridium difficile</i>PCR-027
Highlights
Recommended Citation Drudy, D. et al (2007) GyrA mutations in Fluoroquinolone Resistant Clostridium difficile PCR 027, Emerging Infectious Diseases 13(3),pp.504-5. doi:10.3201/eid1303.060771
We report the mechanism of fluoroquinolone resistance in a cluster (n = 5) of Irish PCR ribotype 027 (PCR-027) C. difficile isolates that were characterized by using toxinotyping and 16–23S ribotyping
This report identifies for the first time a mutation in gyrA that is associated with high-level resistance to fluoroquinolones in C. difficile PCR-027
Summary
Recommended Citation Drudy, D. et al (2007) GyrA mutations in Fluoroquinolone Resistant Clostridium difficile PCR 027, Emerging Infectious Diseases 13(3),pp.504-5. doi:10.3201/eid1303.060771. Lorraine Kyne Mater Misericordiae University Hospital, Rebecca O’Mahony University College Dublin Recommended Citation Drudy, D. et al (2007) GyrA mutations in Fluoroquinolone Resistant Clostridium difficile PCR 027, Emerging Infectious Diseases Several C. difficile outbreaks due to PCR ribotype 027 (PCR-027) and associated with increased disease severity and death have been reported worldwide [4].
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