Abstract
In this study, seasonal variations of antioxidant enzyme activities (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and glucose 6-phosphate dehydrogenase (G6PD)) and malondialdehyde (MDA) levels in gill, kidney, muscle and liver tissues of Garra rufa (Heckel, 1843) caught from Göynük Stream, one of the most important branch of Murat River, were investigated. Fish samples were caught from two stations (Garip and Ilıcalar), which are determined regularly every month, and brought to the laboratory. The levels of biomarkers in tissues were determined by spectrophotometric methods. It was determined that the difference between the parameters in the studied tissues was statistically significant (P < 0.05) between the two stations, but the difference between the stations in the liver tissue in all seasons in GR enzyme was not statistically significant. However, it was determined that the differences between the seasons were significant in both stations. GR and G6PD enzyme activities were found to be lower than other enzyme activities among the enzyme groups studied, but CAT and SOD enzyme activities were found to be higher than the other enzymes., enzyme activities in muscle tissue are lower than activities in the other tissues among tissues.
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