Abstract
To explore the effect of downregulation of β1-AR in myocardium of SHRs on antihypertensive effect. The recombinant plasmid pAAV-ZsGreen-ADRB1-shRNA was confirmed by enzyme digestion and gene sequencing. The plasmid was then packaged to recombinant adeno-associated virus named AAV9- shRNA-ADRB1-
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