GW24-e3078 Vascular peroxidase 1 is involved in pulmonary arterial hypertension via mediate pulmonary arterial smooth cells proliferation

Abstract

ObjectivesHypoxia could induce pulmonary arterial smooth muscle cells (PASMCs) proliferation via hydrogen peroxide (H2O2)-induced oxidative stress. Our previous research had demonstrated that vascular peroxidase 1 (VPO1) could utilise hydrogen peroxide...