Abstract
'Gut health' is a term increasingly used in the medical literature and by the food industry. It covers multiple positive aspects of the gastrointestinal (GI) tract, such as the effective digestion and absorption of food, the absence of GI illness, normal and stable intestinal microbiota, effective immune status and a state of well-being. From a scientific point of view, however, it is still extremely unclear exactly what gut health is, how it can be defined and how it can be measured. The GI barrier adjacent to the GI microbiota appears to be the key to understanding the complex mechanisms that maintain gut health. Any impairment of the GI barrier can increase the risk of developing infectious, inflammatory and functional GI diseases, as well as extraintestinal diseases such as immune-mediated and metabolic disorders. Less clear, however, is whether GI discomfort in general can also be related to GI barrier functions. In any case, methods of assessing, improving and maintaining gut health-related GI functions are of major interest in preventive medicine.
Highlights
In recent times, the term ‘gut health’ has become increasingly popular, as is evident by its more frequent use in the scientific literature and in the food industry [1]
According to the World Health Organisation (WHO) definition of ‘health’ from 1948, which proposes a positive definition instead of ‘the absence of diseases’, one might define gut health as a state of physical and mental well-being in the absence of GI complaints that require the consultation of a doctor, in the absence of indications of or risks for bowel disease and in the absence of confirmed bowel disease
Summary The term ‘gut health’ has become popular; from a scientific point of view, the term is poorly defined and used in different contexts. It covers all aspects, ranging from the Asian understanding of the gut as the middle of spiritual and physical strength to the Western understanding of the GI barrier as a central body site interacting with the environment and involved in the pathophysiology of many intestinal and extraintestinal diseases
Summary
Western world as a desirable aim and an important physiological condition required for overall good health. A growing number of people do not enjoy good gut health, as is indicated by the high prevalence of functional and organic gastrointestinal (GI) diseases in the Western world. From a scientific point of view, it is still very unclear what gut health is, how it can be defined and how it can be measured. Current knowledge of gut health is summarised. Particular emphasis is given to the definition of the term, the underlying mechanisms, how to assess it and how to maintain it. The possible impact of gut health for future, prevention-oriented medicine, as well as the need to increase understanding of this condition and to maintain it, is discussed
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
