Abstract
The microbiota that populate human intestinal tracts vary substantially from person to person, and mounting evidence suggests these interindividual variations in gut microbiota affect how a person metabolizes chemicals they may be exposed to. A review of the literature on this topic directed attention to a new hypothesis: that interactions between gut ecology and environmental chemicals contribute to obesity and diabetes [EHP 120(3):332–339; Snedeker and Hay]. No study has yet directly addressed that hypothesis, but this review comments on the strengths and weaknesses of studies linking environmental chemicals to obesity and diabetes and identifies gaps in the knowledge of how gut microbiota may affect the metabolism of these chemicals.
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