Abstract

The gut microbiome is a critical modulator of systemic physiology, including infectious disease susceptibility. Although this niche is a reservoir for uropathogenic Escherichia coli, knowledge of its role in urinary tract infections (UTIs) is limited. We discuss two recent studies, Thänert etal. (2022) and Worby etal. (2022), that interrogate the roles of the gut-bladder axis in UTIs.

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