Gustatory neuron types in the periphery: A functional perspective

Abstract

Robert P. Erickson's research and writings formed the intellectual backdrop and guiding force for much of the major research on sensory coding in taste. As articulated best by Erickson, consideration focused on the relative merits of labeled-line and across-fiber pattern theory. The present article focuses primarily on a review of the electrophysiological and behavioral studies on salt taste and salt taste-mediated behavior in rodents. The evidence clearly shows that the peripheral gustatory system consists of a few neuron types/groups with well-defined physiological response characteristics. Electrophysiological studies of the chorda tympani nerve define a physiological group of narrowly tuned neurons selectively responsive to NaCl stimuli. It appears that this is a sodium-sensing module that functions primarily in the detection, recognition, and ingestion of NaCl.