Abstract
Guillain-Barré syndrome (GBS) in an immune mediated disease that affects peripheral nerves with possible life-threatening complications. GBS has multiple subtypes including acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor sensory axonal neuropathy (AMSAN), which can make GBS difficult to diagnose. GBS commonly presents after viral infections such as influenza virus, campylobacter jejuni, and zika virus. GBS commonly presents with a prolonged clinical course leading to increased morbidity among affected patients. It is not surprising that COVID-19 has been connected with multiple cases of GBS, which may alter the recovery course for several patients post-COVID. In this report, we present a case of 69-year-old-female who presented with progressive motor weakness and loss of sensation in her extremities after testing positive for antibodies to COVID-19 one-month prior to presentation. Her presentation and treatment of GBS in the setting of COVID-19 is an example of one of the many COVID-19 complications and sheds light on the prolonged recovery course that we may experience as clinicians in the wake of this pandemic.
Highlights
Coronavirus disease 19 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]
While SARS-CoV2 has been observed to cause a respiratory illness in many cases, neurological complications of the virus have been increasingly reported, especially in those patients with more severe infection
A viral pandemic is often linked to a rise in cases of Guillain-Barré syndrome (GBS) as seen with recent outbreaks of zika virus and Middle East respiratory syndrome virus (MERS-CoV) [7,8,9]
Summary
Neuromuscular disorder classically characterized by an acute, ascending paralysis after a recent bacterial or viral infection. A viral pandemic is often linked to a rise in cases of GBS as seen with recent outbreaks of zika virus and Middle East respiratory syndrome virus (MERS-CoV) [7,8,9]. We present an atypical case of GBS secondary to COVID-19 infection
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