Abstract
Guided-wave optical biosensors are reviewed in this paper. Advantages related to optical technologies are presented and integrated architectures are investigated in detail. Main classes of bio receptors and the most attractive optical transduction mechanisms are discussed. The possibility to use Mach-Zehnder and Young interferometers, microdisk and microring resonators, surface plasmon resonance, hollow and antiresonant waveguides, and Bragg gratings to realize very sensitive and selective, ultra-compact and fast biosensors is discussed. Finally, CMOS-compatible technologies are proved to be the most attractive for fabrication of guided-wave photonic biosensors.
Highlights
Photonic and electronic micro- and nano-sensors are emerging as very attractive devices to be employed in a great number of application fields such as medicine, microbiology, particle physics, automotive, environmental safety and defence.In the last few years, a great effort has been devoted to sensor and actuator monolithic integration and micro-electro-mechanical system (MEMS) and micro-opto-electro-mechanical system (MOEMS) development
We investigate the wide spectrum of integrated photonic sensors proposed in literature, including those based on interferometer, hollow and antiresonant waveguides, employing Bragg gratings, adopting Surface Plasmon Resonance, and microcavities based on guided-wave sensors
The charge density wave is associated with an electromagnetic wave, whose field vectors reach its maximum at the interface and evanescently decays into both media. This surface plasma wave (SPW) is a TMpolarized wave
Summary
Photonic and electronic micro- and nano-sensors are emerging as very attractive devices to be employed in a great number of application fields such as medicine, microbiology, particle physics, automotive, environmental safety and defence. Sensors 2007, 7 immunity to electromagnetic interference, good compactness and robustness and high compatibility with fibre networks, and because they usually exhibit shorter response time and higher sensitivities with respect to MEMS/MOEMS devices. A biosensor is a device which consists of a biologically or biophysically-derived sensing element (usually named bio receptor) integrated with a physical transducer that transforms a measurand into an output signal (Fig. 1). Transduction mechanisms are usually electrochemical, mass-based or optical. Electrochemical detection is commonly based on the chemical potential of particular species in solution (analytes) measured by comparison with a reference electrode. We investigate the wide spectrum of integrated photonic sensors proposed in literature, including those based on interferometer, hollow and antiresonant waveguides, employing Bragg gratings, adopting Surface Plasmon Resonance, and microcavities based on guided-wave sensors
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
