Guest-induced supramolecular helices and its application in L-Arg detection and L-Arg controlled reversible morphology modulation

Abstract

A novel AIE supramolecular polymer (BPK) was synthesized by bis(2-hydroxy-1-naphthaldehyde) terephthalo hydrazone functionalized pillar [5]arene and cross-linked using a bis(4.4-dipyridinium salt)cross-linker via host-guest complexation. BPK exhibited strong aggregation-induced emission (AIE) in binary solutions of DMSO/H2O. BPK could be an AIE-based sensor with specific fluorescence sensing ability for L-Arg in water. The detection limit of BPK for L-Arg was 3.95 × 10−7 M, and other amino acids did not interfere with the sensing process. Moreover, in a pure DMSO solvent, BPK can self-assemble into a fibrous structure of the right-hand spiral by guest-induced supramolecular helices. At 80 % water content, BPK undergoes a morphological transformation into supramolecular polymer. Intriguingly, BPK exhibits a reversible transformation from a polymer to a nanosphere through the alternating addition of trifluoroacetic acid and arginine. Additionally, the fluorescence of BPK demonstrates an "on-off" switch. This phenomenon is attributed to the formation and disruption of intermolecular hydrogen bonds. The reversible manipulation of polymer materials' morphology and optical properties holds significant potential in biomedicine and smart materials.