Abstract

High levels of cyclic guanosine 3' : 5'-monophosphate (cyclic GMP) activity were detected in the fruit of Zizyphus jujuba. A cyclic GMP-like substance was separated from cyclic adenosine 3' : 5'-monophosphate (cyclic AMP), which is also present in the same plant. The levels of cyclic GMP in the fruits of Zizyphus jujuba range from 30 to 60 mol/g (dry wt.) ; these values are the highest yet found, either in plants or in animal tissue. The partially purified cyclic GMP-like substance was identical with authentic cyclic GMP as judged by thin layer chromatography using different solvents and by spectroscopy, and was decomposable by cyclic nucleotide-specific phosphodiesterase.

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