Abstract

Particle focusing into a specific area in a microchannel is especially important for precise particle detection, separation and sorting in various microfluidic devices for biomedical diagnostics and cell biology. In recent years, although various particle focusing approaches in microchip have been reported, they have some problems such as complicated fabrication and peripherals. This study suggests an innovative three-dimensional (3D) hydrodynamic particle focusing technique applicable in wide Re with only two inlets. The performances of the particle focusing m under different flow rates and channel shapes were evaluated by numerical simulation. In addition, experimental evaluation of the focusing was performed by particle speed measurement. As a result, we confirmed the validity of the proposed particle focusing technique.

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