Abstract
SummaryThe guanine analog, 8-azaguanine, had a growth inhibiting effect on one species of suctorian, Tokophrya injusionum, and a growth promoting effect on another species, Podophrya collini. The compound induced abnormal giant forms in the former and prevented their appearance in the latter. Guanylic acid antagonized both effects. In the hypotrichous ciliate, Stylonychia pustulata 8-azaguanine promoted growth and substituted for a supplementary factor previously obtained from natural sources. The methyl-purines, caffeine, theobromine and theophylline were also growth promoting in Podophrya and Stylonychia. The results may be explained on the basis of a purine balance in these protozoa. Apparently guanylic acid intake in other than optimum proportions can interfere with growth in the organisms studied.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
