Growth performance, gastrointestinal microbial activity, and immunological response of piglets receiving microencapsulatedEnterococcus faecalisCG1.0007 and enzyme complex after an oral challenge withEscherichia coli(K88)

Abstract

The aim of this study was to determine effects of dietary microencapsulated Enterococcus faecalis CG1.0007 probiotic and multienzyme complex (MC) in Enterotoxigenic Escherichia coli K88 (ETEC) challenged piglets. Thirty-six, 21-d-old weanling pigs were randomly allotted to four dietary treatments: a wheat–barley based negative control (NC), NC + MC, NC + probiotic, and NC + MC + probiotic. After 7-d acclimatization to treatments, pigs were weighed, blood was sampled, and then the pigs were orally challenged with an ETEC inoculum. After the challenge, blood was sampled at different time points; performance measures and fecal consistency scores were recorded; and on day 14, all pigs were killed to obtain intestinal tissue samples. During prechallenge, pigs receiving enzyme, probiotic, and a combination of both showed a significant improvement in daily gain (P = 0.03) and feed efficiency (P = 0.04) compared with control. During the postchallenge period, a greater (P = 0.05) ileal villus height was observed for diets supplemented with probiotic alone. Overall, pigs fed diets with probiotic alone also showed less incidence of diarrhea (P = 0.04) compared with control. In summary, the results indicate that dietary supplementation with microencapsulated Enterococcus faecalis CG1.0007 in weaned piglets challenged with ETEC was effective in controlling diarrhea.