Abstract
Segments of the organ of Corti with its innervation preserved were excised from the newborn mouse and studied in culture. The following growth patterns were observed: (a) maintenance of the normal innervation pattern and growth along normal lines if the hair cells remain in their usual location, (2) growth by elongation of the fiber if the hair cells migrate into the out‐growth zone and if the fiber remains in contact with the receptor, and (3) free growth of the fiber if its connections with the hair cells are broken. Growth by elongation is confined to the area of hair cell displacement. The growth is well organized and the length of the fiber compensates strictly for the distance the respective hair cell has migrated. Free growth proceeds at a faster rate then does growth by elongation, is independent of the receptors, is unrestricted in length, and uncontrolled in amount. The growth is disorganized and luxuriant for at least several weeks after explanation. [Work supported by NIH grants NS08626 and NS12732.]
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
