Growth of the P388 leukemia as an ascites tumor in zinc-deficient mice.

Abstract

SummaryThe growth of P388 leukemia cells as an ascites tumor is markedly depressed in mice fed a zinc-deficient diet. Tritiated-thymidine labeling data suggest that zinc-deficient tumor cells accumulate in G1.We acknowledge with thanks the expert technical assistance of Mr. J. Meneses. DHB was supported by U.S. Public Health Service Medical Student Summer Research Fellowship No. FR 05355-10. Work performed under the auspices of the U.S. Atomic Energy Commission.