Abstract
Background Single ventricle heart defects affect 2 per 1000 live births in the US and are lethal if left untreated. The Fontan procedure used to treat these defects consists of a series of palliative surgeries to create the total cavopulmonary connection (TCPC) which bypasses the right heart. In the last stage, the inferior vena cava (IVC) is connected to the pulmonary arteries (PAs) using one of two main approaches: an extracardiac conduit (EC), where a synthetic graft is used as the conduit; and the lateral tunnel (LT), where the atrial wall is used along with a synthetic patch to create the pathway. The LT pathway is anticipated to grow in the long term because it is formed partially with native atrial tissue, as opposed to the EC that retains its original size (contains only synthetic material); however, growth of LT pathways has not been systematically quantified. The objective of this work is to quantify cavopulmonary pathway growth from serial MR images of LT patients.
Highlights
Single ventricle heart defects affect 2 per 1000 live births in the US and are lethal if left untreated
The inferior vena cava (IVC) is connected to the pulmonary arteries (PAs) using one of two main approaches: an extracardiac conduit (EC), where a synthetic graft is used as the conduit; and the lateral tunnel (LT), where the atrial wall is used along with a synthetic patch to create the pathway
The anatomy was reconstructed using state of the art techniques developed in our research group; the inferior cavopulmonary pathway was isolated by cutting above the inferior venous confluence and before the
Summary
Single ventricle heart defects affect 2 per 1000 live births in the US and are lethal if left untreated. The Fontan procedure used to treat these defects consists of a series of palliative surgeries to create the total cavopulmonary connection (TCPC) which bypasses the right heart. The inferior vena cava (IVC) is connected to the pulmonary arteries (PAs) using one of two main approaches: an extracardiac conduit (EC), where a synthetic graft is used as the conduit; and the lateral tunnel (LT), where the atrial wall is used along with a synthetic patch to create the pathway. The LT pathway is anticipated to grow in the long term because it is formed partially with native atrial tissue, as opposed to the EC that retains its original size (contains only synthetic material); growth of LT pathways has not been systematically quantified. The objective of this work is to quantify cavopulmonary pathway growth from serial MR images of LT patients
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