Abstract

Several data on the growth of Myc. lepraemurium in the experimental mouse and rat by inoculation through subcutaneous, intraperitoneal, intracerebral, intratesticular, and intravenous routes, respectively, have been already reported. The factors influencing the susceptibility of mice, especially the kinds of mouse strains, to the bacilli were vigorously studied by several investigators in order to determine the optimal conditions for the screening test of chemical agents against murine leprosy using experimental mice. However, there have been no reports, so far, concerning the growth of Myc. lepraemurium in mice transplanted with malignant tumor. The present paper reports the investigation of a relationship between murine leprosy and Ehrlich ascites tumor inoculated into the mice by the same routes at a different or at the same time.

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