Abstract
The inhibition of Clostridium thermocellum strains by acetate and other organic acids (propionate, butyrate) can be explained by a model based on the chemiosmotic theory and uncoupler action. It is proposed that the charged permeant species in the process of anion exclusion is the dimer HA - 2 . Evidence for this mechanisms is provided by 31P-NMR studies of whole cells and cell extracts.
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