Growth in Asthmatic Children Treated with Fluticasone Propionate

Abstract

1. David BA, 2. Edwin AB, 3. Craig FL, 4. Robert AN, 5. David GT, 6. Mark LV, 7. Peter K, 8. and the Fluticasone Propionate Asthma Study Group (1998) J Pediatr. 132:472–477. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] #### Purpose of the Study To determine whether inhaled fluticasone propionate (FP) has long-term effects on growth in children with persistent asthma. ##### Study Population Three hundred twenty-five prepubescent children 4 to 11 years of age with persistent asthma and in the recent past normal growth rates. ##### Methods The patients were divided into three groups; 106 patients received placebo, 111 patients received FP 50 μg bid, and 108 patients received FP 100 μg bid via a diskhaler. Of 325 patients, 57 showed signs of puberty during the study (19 from the placebo group, 26 from the FP 50 μg group, 12 from the FP 100 μg group) and were excluded from … [1]: {openurl}?query=rft.jtitle%253DThe%2BJournal%2Bof%2Bpediatrics%26rft.stitle%253DJ%2BPediatr%26rft.aulast%253DAllen%26rft.auinit1%253DD.%2BB.%26rft.volume%253D132%26rft.issue%253D3%2BPt%2B1%26rft.spage%253D472%26rft.epage%253D477%26rft.atitle%253DGrowth%2Bin%2Basthmatic%2Bchildren%2Btreated%2Bwith%2Bfluticasone%2Bpropionate.%2BFluticasone%2BPropionate%2BAsthma%2BStudy%2BGroup.%26rft_id%253Dinfo%253Adoi%252F10.1016%252FS0022-3476%252898%252970023-X%26rft_id%253Dinfo%253Apmid%252F9544904%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1016/S0022-3476(98)70023-X&link_type=DOI [3]: /lookup/external-ref?access_num=9544904&link_type=MED&atom=%2Fpediatrics%2F104%2FSupplement_2%2F389.3.atom [4]: /lookup/external-ref?access_num=000072877800023&link_type=ISI