Abstract
IN addition to promoting linear growth in prepubertal children, growth hormone is often described as having anabolic, lipolytic, and diabetogenic properties. These descriptions are based on the results of diverse short-term studies of humans, animals, and isolated tissues, many of which involved the use of large doses of growth hormone. Until the production of growth hormone by recombinant-DNA methods began, the small supply of pituitary-derived human growth hormone limited its use to the treatment of children with growth hormone deficiency. The wide availability of synthetic human growth hormone has made possible long-term studies of other potentially beneficial uses of growth . . .
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