Abstract

This review highlights current concepts of physiological and pathophysiological effects of growth hormone on the heart. The data of international clinical studies concerning the influence of GH deficit and excess on the cardiovascular system are discussed with special reference to such clinical conditions as somatotrophic pituitary insufficiency and acromegaly. Result of analysis of parameters of the cardiovascular system in the patients receiving growth hormone substitution therapy for somatotrophic insufficiency and GH-suppressive therapy of acromegaly are presented

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