Abstract
Observed changes in the reactivity of the essential sulfhydryl groups of a protein growth factor correlate with changes in its biological activity. In activated and non-activated growth factor, the maximal number of sulfhydryl groups reacting with parachloromercuribenzoate was the same; while the spatial arrangement of the sulfhydryl groups appeared to differ, as evidenced by their different rates of chemical reaction. It is believed that these changes in sulfhydryl reactivity reflect structural changes in the protein molecule and that these structural changes are responsible for the observed changes in its biological activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
