Growth Dysregulation in Cancer Cells

Abstract

This chapter discusses about the growth rate of cancer cells. A most important characteristic of cancer cells is their growth at the wrong places and times. A wound generates new cells until it has healed. But in cancer, cell growth does not stop. The chapter then discusses the author's college life and graduate training. It also describes the author's cancer research in 1950. The chapter also discusses about regulatory processes and regulations in higher organisms. Cancer and the cell surface are discussed briefly in the chapter. The restriction point hypothesis is also described in the chapter. The chapter then moves on to the discussion of a short-lived regulatory protein. Transcription from the promoter region of the mouse thymidine kinase (TK) gene and Yi complexes are discussed next. Cyclin E as a candidate R-point protein and cyclin changes in breast cells are also discussed in the chapter. It has also described breast cancer in vivo also. Finally, the chapter ends with the discussion of the future problems of growth dysregulation of the cancer cells.