Abstract
As one of a series of integrated reports regarding the role of thyroid in growth and metabolism of normal and I131thyroid-ablated infant rhesus monkeys,1this communication presents quantitative aspects of iodine metabolism. Earlier reports of thyroid function in rhesus monkeys are limited to observations on thyroidectomized mature animals,2except in the study of Fleischmann and (Footnotes continued on next page) co-workers,2awhere two 8-month-old animals were also observed. Of the reported studies,2none have dealt with iodine metabolism per se, nor have they been concerned with the role of thyroid in growth and development. In all cases, thyroidectomy was achieved either by prolonged administration of thiouracil3or by surgical means—the latter frequently being complicated by severe and often fatal hypoparathyroidism.4When thiouracil was used, large doses (0.8 gm. per day) were found necessary to produce hypothyroidism and thyroid hyperplasia in adult animals,
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