Abstract
The growth advantage in stationary phase (GASP) phenomenon is defined as fluctuations in viable cell numbers during stationary phase growth; a rapid loss of viability followed by an increase in viable counts.1 GASP was first reported in Escherichia coli when cells from a 10-day-old culture were able to out-compete cells from a 1-day-old culture if introduced as a minority.2 The reason for this population takeover is considered to be due to a series of genetic changes, which occur upon entry into stationary phase and to the physiological and structural alterations that occur and induce higher levels of resistance to a range of environmental stresses.
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