Abstract
Interneurones mediating disynaptic inhibition from extensor to flexor carpi radialis muscles were characterized by pharmacological stimulation of Renshaw cells. It is, indeed, known that only la interneurones are blocked by recurrent inhibition. Renshaw cell potentiation, induced by intravenous administration of 2 g levo-acetylcarnitine, blocked Ia reciprocal inhibition from triceps to biceps muscles but not disynaptic inhibition from extensor to flexor carpi radialis muscles. It is concluded that the interneurones mediating this latter inhibition are not Ia intemeurones. This kind of inhibition could be an example of a Ia non-reciprocal inhibitory pathway.
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