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Group-Based Trajectory Modeling: An Overview

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Abstract
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This article provides an overview of a group-based statistical methodology for analyzing developmental trajectories - the evolution of an outcome over age or time. Across all application domains, this group-based statistical method lends itself to the presentation of findings in the form of easily understood graphical and tabular data summaries. In so doing, the method provides statistical researchers with a tool for figuratively painting a statistical portrait of the predictors and consequences of distinct trajectories of development. Data summaries of this form have the great advantage of being accessible to nontechnical audiences and quickly comprehensible to audiences that are technically sophisticated. Examples of the application of the method are provided. A detailed account of the statistical underpinnings of the method and a full range of applications are provided by the author in a previous study.

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Due to the popularization of Android and the full range of applications (apps) targeting this platform, many security issues have emerged, attracting researchers and practitioners' attention. As such, many techniques for addressing security Android issues have emerged, including approaches for mining sandboxes using dynamic analysis tools (i.e., automated testing tools). Undoubtedly, the resulting sandboxes' efficiency depends on the test case generation tools used in the mining procedures. Previous research studies have compared Android test case generation tools for this specific goal. However, it is difficult to increment the research in this field because reproducing these previous empirical studies is a challenging and time-consuming task. This difficulty occurs because it is necessary to integrate test generation tools that often require different and conflicting versions of the Android platform, programming languages (e.g., Python 2 and Python 3), and software libraries. To mitigate this issue, in this paper we present DroidXP, a software infrastructure that allows researchers (and tools developers) to integrate and compare test case generation tools for mining sandboxes. We evaluated DroidXP through a reproduction study of previous research work, though considering additional test case generation tools. Our experiment suggests that DroidXP simplifies the comparison of existing tools for mining sandboxes, and revealed that Sapienz outperforms the other test case generation tools-regardless of the Monkey tool had presented the highest code coverage in our study.

  • Book Chapter
  • Cite Count Icon 17
  • 10.1007/978-1-4419-0245-0_4
Group-Based Modeling: An Overview
  • Jan 1, 2009
  • Daniel S Nagin

This chapter provides an overview of a group-based statistical methodology for analyzing developmental trajectories—the evolution of an outcome over age or time. A detailed account of the method’s statistical underpinnings and a full range of applications are provided in Nagin (2005). In this discussion, the term developmental trajectory is used to describe the progression of any phenomenon, whether behavioral, biological, or physical. Charting and understanding developmental trajectories is among the most fundamental and empirically important research topics in the social and behavioral sciences and medicine. A few prominent examples include the following: criminological analyses of the progression and causes of criminality over life stages or of time trends of reported crime across geographic locations, psychological studies of the course and antecedents of psychopathologies, sociological investigations into the interaction between human behavior and social context over time, and medical research on the impact of treatments on the progress of diseases. Longitudinal data—data with a time-based dimension—provide the empirical foundation for the analysis of developmental trajectories. Most standard statistical approaches for analyzing developmental trajectories are designed to account for individual variability about a mean

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Due to the popularization of Android and the full range of applications (apps) targeting this platform, many security issues have emerged, attracting researchers and practitioners' attention. As such, many techniques for addressing security Android issues appeared, including approaches for mining sandboxes. Previous research studies have compared Android test case generation tools for this specific goal. Our research aims to explore new techniques for mining sandboxes, especially we are interested in understanding the limits of both static and dynamic analysis in this process. Although the use of tests for mining sandboxes has been explored before, the potential to combine static analysis and dynamic analysis has not been sufficiently investigated yet. That is, in this thesis we will investigate the hypothesis that combining static and dynamic analysis techniques increases the process of mining Android sandboxes.

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Stable carbon isotope ratios (δ(13) C) of terrestrial plants are employed across a diverse range of applications in environmental and plant sciences; however, the kind of information that is desired from the δ(13) C signal often differs. At the extremes, it ranges between purely environmental and purely biological. Here, we review environmental drivers of variation in carbon isotope discrimination (Δ) in terrestrial plants, and the biological processes that can either damp or amplify the response. For C3 plants, where Δ is primarily controlled by the ratio of intercellular to ambient CO2 concentrations (ci /ca ), coordination between stomatal conductance and photosynthesis and leaf area adjustment tends to constrain the potential environmentally driven range of Δ. For C4 plants, variation in bundle-sheath leakiness to CO2 can either damp or amplify the effects of ci /ca on Δ. For plants with crassulacean acid metabolism (CAM), Δ varies over a relatively large range as a function of the proportion of daytime to night-time CO2 fixation. This range can be substantially broadened by environmental effects on Δ when carbon uptake takes place primarily during the day. The effective use of Δ across its full range of applications will require a holistic view of the interplay between environmental control and physiological modulation of the environmental signal.

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Orthoses have evolved from simply maintaining bone fractures and correcting spinal deformities to full mechatronic systems that can read a person’s intention and translate that into a desired motion or force path. A vast variety in pathologies (e.g., stroke, muscular dystrophies), applications (e.g., daily assistance, research) and environments (e.g., home, clinic) are possible. The term dynamic hand orthosis is able to cover this full range of applications and is therefore used as an umbrella term. In order to map the research field of dynamic hand orthosis and improve on the state-of-the-art, this thesis proposes a design methodology that categorizes mechatronic components and collects rationale to make specific design choices through scoping a optimization. Finally, a proof-of-principle dynamic hand orthosis was made and tested on a single participant in a case study experiment.

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Review: ca. 80 refs.

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