Group B streptococcus infection in late trimester of pregnancy and its influence on maternal-neonatal outcomes in Zhenjiang

Abstract

Objective To discuss group B streptococcus (GBS) infection in late trimester of pregnancy and its influence on maternal-neonatal outcomes in Zhenjiang. Methods A total of 10 458 women at 35-37 weeks pregnant, during January 2016 to August 2018 in Zhenjiang, were selected as research objects. GBS specific gene (CAMP) of vaginal and perianal swab secretions was detected by polymerase chain reactio (PCR) and fluorescent labeled probe. One hundred GBS positive patients were allocated into observation group and 150 GBS negative pregnant women were randomly selected as control group. The rate of GBS infection in pregnant women was calculated and the pregnancy outcomes and neonatal infection were analyzed. Results The rate of GBS infection in pregnant women was 4.84% in Zhenjiang. The incidences of threatened premature labor, premature rupture of membranes, neonatal infection, pneumonia of newborn and low birth weight infant in observation group were higher than those in control group, and the difference was significant (P 0.05). Conclusions GBS infection in late trimester of pregnancy will increase the incidences of threatened premature labor, premature rupture of membranes, neonatal infection, pneumonia of newborn and low birth weight infant. Key words: Late trimester of pregnancy; Group B streptococcus; Pregnancy outcomes