Abstract
We present a 73-year-old female with advanced thyroid papillary carcinoma who complained of gross hematuria. We found a bladder tumor and considered it the cause of her symptom. Cystoscopic findings of the tumor were unusual, with peri-tumor vessel formation. Pathological examination of the bladder tumor was consistent with metastasis of thyroid papillary carcinoma. Therefore, we identified thyroid carcinoma metastasis to the urinary bladder as the cause of hematuria in our patient. Thyroid carcinoma metastasis to the bladder is extremely rare, but it should be included among differential diagnoses for gross hematuria in patients with a clinical history of thyroid carcinoma.
Highlights
Well-differentiated thyroid cancer is an indolent malignancy derived from the thyroid epithelial cells [1]
As far as we know, only two cases who developed metastatic bladder tumor caused by well-differentiated thyroid cancer have been reported [3, 4]
There are several similarities in patients with metastatic bladder tumor caused by well-differentiated thyroid cancer
Summary
Well-differentiated thyroid cancer is an indolent malignancy derived from the thyroid epithelial cells [1]. Common sites of distant metastasis are the lung and the bone followed by the brain [2]. Other sites of metastasis are rare and may indicate even more advanced disease. Well-differentiated thyroid cancer includes both thyroid papillary carcinoma and thyroid follicular carcinoma, the biological behaviors of which are known to differ. Thyroid follicular carcinoma tends to cause blood-borne metastasis, but thyroid papillary carcinoma tends to cause lymphatic metastasis with common recurrence in the neck lymph nodes [1]
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