Grisan derivatives in pure and mixed monomolecular films

Abstract

Pressure-area isotherms for monolayers of two synthetic grisan derivatives have been determined and correlated with molecular orientations of these entities at the air-water interface. Isotherms for equimolar mixtures of the grisan derivatives with stearic acid, cholesterol, and l-α-lecithin, respectively, are reported. The pressure-area curves show, in general, the predominant influence of the grisan derivatives at low pressures, and ejection of these from the monolayer at intermediate pressure values. At higher pressures the curves reflect largely the properties of the respective lipids. Theoretical curves for the mixtures were calculated assuming additivity, and compared with the corresponding experimentally derived isotherms.