Abstract
We examined whether functional and structural variability in the primary visual area (V1) correlated with autism traits. Twenty-nine participants (16 males; MAge = 26.4years, SDAge = 4.0years) completed the autism-spectrum quotient (AQ) questionnaire prior to a magnetic resonance imaging session. The total AQ scores was used to assess the degree of self-reported autism traits. The average functional activation in V1 to visual stimulation and its average grey-matter thickness were calculated. There were no correlations between functional activation in V1 and autism traits. Conversely, grey-matter thickness of the left but not the right V1 correlated with autism traits. We conclude that structural changes in the left V1 could be a marker for the presence of autism traits.
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