Abstract

Grewia asiatica L., is a species native to south Asia from Pakistan, east to Cambodia, cultivated primarily for its edible fruit and well-reputed for its diverse medicinal uses. Fruits are a rich source of nutrients such as proteins, amino acids, vitamins, and minerals and contain various bioactive compounds, like anthocyanins, tannins, phenolics and flavonoids. Different parts of this plant possess different pharmacological properties. Leaves have antimicrobial, anticancer, antiplatelet and antiemetic activities; fruit possess anticancer, antioxidant, radioprotective and antihyperglycemic properties; while stem bark possesses analgesic and anti-inflammatory activities. This review focuses on the botanical description, phytochemistry, nutritional studies and pharmacological properties of this plant.

Highlights

  • The dieto-therapeutic importance of fruits is well-recognized since the beginning of human civilization

  • As a step in this direction and as part of our studies [4,5,6,7,8,9,10,11] on documenting biological and chemical studies of indigenous flora of Pakistan, we have reviewed the phytochemistry, nutritional importance and pharmacological properties of this plant

  • The irradiation of animals resulted in a significant elevation of lipid peroxidation in terms of thiobarbituric acid reactive substances (TBARS) content and depletion in glutathione (GSH) and protein levels, as compared to control group

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Summary

Introduction

The dieto-therapeutic importance of fruits is well-recognized since the beginning of human civilization. Molecules 2013, 18 countries and there is a growing interest in exploring their therapeutic and nutritional properties. Grewia asiatica L., grows wildly, and is cultivated in south Asian countries. The name Grewia was given due to Nehemiah Grew, one of the founders of plant physiology, while asiatica reflects the. As a step in this direction and as part of our studies [4,5,6,7,8,9,10,11] on documenting biological and chemical studies of indigenous flora of Pakistan, we have reviewed the phytochemistry, nutritional importance and pharmacological properties of this plant. This review will serve as a useful reference for further research on this important plant

Botanical Description and Traditional Uses
Compositional Studies
Preliminary Phytochemical Screening and Primary Metabolites
Compounds Isolated and Secondary Metabolites
Antioxidant Activity
Radioprotective Effect
Anticancer Activity
Antimicrobial Activity
Antiviral Activity
Antihyperglycemic and Antidiabetic Activity
Effect on Glycemic Index
Anti-Hyperlipidemic Activity
Analgesic activity
4.10. Antipyretic Activity
4.11. Anti-Inflammatory Activity
4.12. Antimalarial and Antiemetic Activities
4.13. Antiplatelet Activity
4.14. Other Activities
Adsorption Studies
Findings
Conclusions
Full Text
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