Abstract

Proof of principle is demonstrated for a novel approach for using pressurized liquid carbon dioxide (CO2) as a mobile phase for flash chromatography purification, rather than traditionally used organic solvents. Regulation of a pressurized CO2 supply line rather than specialized and expensive CO2 pumps and chillers typically used in supercritical fluid chromatography applications greatly simplifies operations while reducing costs. Evaluation of a prototype instrument reveals encouraging purification, recovery, and reduction in organic solvent usage.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.