Greener and efficient synthesis of Benzodiazepines using mixed Ferrite under solvent free condition

Abstract

The Ferrite material Zn0.6Ni0.2Cu0.2Fe2O4 was synthesized by the sol-gel auto combustion method and characterized by its TG and DTA. The crystallographic structures were studied by XRD. Morphology and structure of the powder samples were studied by SEM and TEM. The synthesis of benzodiazepines via one-pot two-component condensation reaction of o-phenylene diamine and ketones carried by using synthesized ferrite as a recyclable catalyst. This synthetic approach eliminates the use of hazardous organic solvents with the important benefit of easy separation and reusability of the catalyst without compromising the yield or purity