Abstract
The application of green chemistry for the synthesis of nanoparticles is said to be environmentally friendly and cost efficient. The paper reports on the cell anti-proliferative activity of Pechuel-loeschea leubnitziae, synthesis of silver nanoparticles using P. leubnitziae and characterization. The UV–vis spectroscopy confirmed presence of a peak at 400 nm, and Fourier-transform infrared spectroscopy confirmed the presence of peaks from 700-4000 cm−1 correlating to AgNPs. Presence of silver, carbon and oxygen was confirmed by X-ray photoelectron spectroscopy and Energy-dispersive X-ray spectroscopy. Transmission electron microscopy showed a uniform spherical particle in the size of 100 nm, and scanning electron microscope showed spherical particles at a magnification of 100 µm. The extracts and the synthesized AgNPs were tested for cytotoxicity and anti-cancer activity against the Vero and U87 glioma cell lines. The results for both cell lines indicated that dichloromethane extract and AgNPs were cytotoxic and had potential anti-cancer properties.
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