Abstract
Silver ions (Ag+) and its compounds are highly toxic to microorganisms, exhibiting strong biocidal effects on many species of bacteria but have a low toxicity toward animal cells. In the present study, silver nanoparticles (SNPs) were biosynthesized using aqueous extract of Chlorella vulgaris as reducing agent and size of SNPs synthesized ranged between 15 and 47 nm. SNPs were characterized by UV–visible spectroscopy, scanning electron microscopy, transmission electron microscopy, X-ray diffraction and Fourier infrared spectroscopy, and analyzed for its antibacterial property against human pathogens. This approach of SNPs synthesis involving green chemistry process can be considered for the large-scale production of SNPs and in the development of biomedicines.
Highlights
Nanotechnology is an exploitation of strange properties of materials smaller than 100 nm to create new useful objects
silver nanoparticles (SNPs) were characterized by UV–visible spectroscopy, scanning electron microscopy, transmission electron microscopy, X-ray diffraction and Fourier infrared spectroscopy, and analyzed for its antibacterial property against human pathogens
The present study involves the biosynthesis of SNPs where aqueous cell-free extract of C. vulgaris was added to the freshly prepared 1 mM silver nitrate (AgNO3) at different dilution
Summary
Nanotechnology is an exploitation of strange properties of materials smaller than 100 nm (nm) to create new useful objects. Nanomaterials display unique, superior and indispensable properties and have attracted much attention for their distinct characteristics that are unavailable in conventional macroscopic material. Their uniqueness arises from higher surface-to-volume ratio and Silver nanoparticles are nontoxic, safe inorganic antibacterial agent used for centuries and are capable of killing about 650 types of diseases causing microorganisms. Silver has been described as oligodynamic because of its ability to exert a bactericidal effect at minute concentrations. The first scientific papers describing the medical use of silver report the prevention of eye infection in neonates in 1881 and internal antisepsis in 1901 (Russell and Hugo 1994). Silver nitrate and silver sulfadiazine have been widely used for the treatment of superficial and deep dermal burns of wounds and for the removal of warts (Rai et al 2009)
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