Abstract
ABSTRACT Green synthesis of selenium nanoparticles (Se-NPs) was done using Abelmoschus esculentus extract as the capping and reducing agent and sodium selenite (Na2SeO3) as the selenium source. UV-Vis spectrum confirmed the formation of Se-NPs in the solution. According to the XRD pattern, the average particle size was estimated to be about 30.7 nm. The TEM images shown the spherical shape of Se-NPs. The antimycobacterial effects of Se-NPs were tested against the standard strains of Mycobacterium tuberculosis (H37RV) and Mycobacterium simiae isolates. Antibacterial impacts were examined through the usage of resazurin microtiter assay (REMA) against bacterial strains, including Staphylococcus aureus, Streptococcus mutans, Escherichia coli, and Pseudomonas aeruginosa. There were no significant abilities to be reported from the Se-NPs for combating M. tuberculosis H37Rv and M. simiae strains. Based on the results, the nanoparticles displayed stronger antibacterial activities towards the Gram-positive bacteria.
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