Green synthesis of MgO nanoparticles using Moringa oleifera leaf aqueous extract for antibacterial activity

A Fatiqin,H Amrulloh,W Simanjuntak

doi:10.4314/bcse.v35i1.14

Abstract

Nanoparticle fabrication using plant extracts is an important alternative method because it is non-toxic, biocompatible, and environmentally friendly. In this study, green synthesis of MgO nanoparticles using Moringa oleifera leaf water extracts was conducted by mixing the extract and a solution of magnesium chloride. The product was characterized using different techniques, i.e. UV-Visible (UV-Vis) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). The UV-Vis spectrum of MgO nanoparticles shows an absorption at 280 nm. The size of the synthesized MgO nanoparticles ranges from 20-50 nm. The antibacterial activity of MgO nanoparticles was seen from the zone of inhibition against Staphylococcus aureus (6.3 mm) and against Escherichia coli (6 mm). MgO nanoparticles have been successfully fabricated using Moringa oleifera leaf aqueous extracts, providing an alternative method for synthesizing MgO nanoparticles.  KEY WORDS: Antibacterial activity, Escherchia coli, MgO nanoparticles, Moringa oleifera, Staphylococcus aureus  Bull. Chem. Soc. Ethiop. 2021, 35(1), 161-170. DOI: https://dx.doi.org/10.4314/bcse.v35i1.14

Highlights

In recent years, a lot of interest has arisen to synthesize nanoparticles of Fe, Ni, Cu, Ti, and Mg because they have superior properties and can be applied in variousfieldssuch as sensors [1], catalyst [2], and biomedical applications [3,4,5]
The results showed that the magnesium oxide (MgO) produced had high activity as an antibacterial agent against S. aureus with a small dose (250 μg/mL)
Green synthesis of MgO nanoparticles using plant extracts is a good alternative in the synthesis of a metal oxide nanomaterial

Summary

Introduction

A lot of interest has arisen to synthesize nanoparticles of Fe, Ni, Cu, Ti, and Mg because they have superior properties and can be applied in variousfieldssuch as sensors [1], catalyst [2], and biomedical applications [3,4,5]. Ezhilarasi et al [3] successfully synthesized nickel oxide nanoparticles (NiO) using Moringa oleifera leaf extract with water and ethanol as asolvent. The synthesis of MgO nanoparticles was carried out using M. oleifera leaf aqueous extracts and studied the antibacterial activity against E. coli and S. aureus.

Results

Conclusion