Green synthesis of Ionic liquid mediated Ytterbium oxide nanoparticles by Andrographis Paniculata leaves extract for structural, morphological and biomedical applications

Abstract

The eco-friendly synthesis of Yb2O3 and IL-Yb2O3 NPs was performed by Andrographis Paniculata leaves extract. The XRD pattern described the crystalline behavior and the crystallite size was at 50 and 45 nm for Yb2O3 and IL-Yb2O3 NPs. The FTIR and Raman analyses illustrated the functional groups of Yb2O3 and IL-Yb2O3 NPs. The UV–visible analysis described the formation of synthesized NPs with the absorption peak at 227 and 239 nm. The photoluminescence study revealed the yellow color luminescent behavior of Yb2O3 and IL-Yb2O3 NPs. The formation of IL-Yb2O3 NPs with 25–75 nm particle size was revealed from DLS analysis. The SEM analysis explained the circular and rectangular morphology of Yb2O3 and IL-Yb2O3 NPs. The composition analysis of EDX showed the purity of Yb2O3 and IL-Yb2O3 NPs with the presence of only Yb and O peaks and also chemical elements of IL-Yb2O3 NPs was confirmed by XPS analysis. The HRTEM analysis explained the hexagonal structured formation of Yb2O3 and IL-Yb2O3 NPs. The antibacterial assay described the high inhibition of Yb2O3 and IL-Yb2O3 NPs on E.coli and S.aureus bacteria. The anti-diabetic assay revealed the biomedical behavior of Yb2O3 and IL-Yb2O3 NPs on α-Amylase. The anti-inflammatory assay found the potential denaturation of bovine serum albumin (BSA) by Yb2O3 and IL-Yb2O3 NPs. The antioxidant assay revealed the potential free radical scavenging behavior of Yb2O3 and IL-Yb2O3 NPs. The MTT assay found the biomedical potential action of Yb2O3 and IL-Yb2O3 NPs on the MCF-7 cancer cell line.