Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment

Abstract

Nanotechnology has proven to be a technology capable of generating anti-cancer nanoparticles in an environmentally friendly approach. Nanoparticles are usually created using a variety of processes that have a detrimental effect on the environment. Incorporating plant extracts with nanoparticles is an alternative, conservative method. In our research, gold nanoparticles were prepared by two aqueous extracts of Ziziphus spina-christi leaves and Cordia myxa L. leaves, and diagnosed using TEM, FE-SEM and AFM. The ability of gold nanoparticles as an anti-breast cancer agent was tested against MCF-7 cell line in synergistic with near-infrared radiation (NIR) at 808 nm. It was found that radiation enhances the properties of gold nanoparticles as a cancer treatment by converting the absorbed light into heat in a short time through a series of non-radiative processes.