Abstract

In the present investigation, we have described the green biosynthesis of Zinc nanoparticles (ZnNPs) using aqueous root extract of Sphagneticola trilobata Lin as capping agent. The antioxidant, anti-diabetic and antimicrobial activities of ZnNPs was also studied. The Scanning Electron Microscopy analysis (SEM) results confirmed the irregular shaped of AgNPs with difference sizes of the particles and an average from 65–80 nm. X-ray diffraction (XRD) result confirmed the characteristic peaks indicated at 111, 200, 221 and 311 crystal planes for the crystalline of the face centered cubic lattice. Further, aqueous root extract extract and ZnNPs were evaluated to assess their antioxidant potential using various in vitro systems such as using 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2, 2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and Hydroxyl radical scavenging activity. The anti-diabetic and anti-inflammatory activity of the aqueous root extract and ZnNPs were also studied and the results confirm the Zinc nano particles synthesized using aqueous root extract of Sphagneticola trilobata Lin were found to having enhanced pharmacological activities.

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