Abstract
Background: Nanotechnology is one the most crucial areas of research with a wide biomedical application including drug delivery. Conventionally physical, and chemical methods have been used for the synthesis of metal-based nanoparticles (NPs) however, they show cytotoxicity and even not better for sustainable environment. Therefore, green synthesis of NPs using plant extract is a better alternative. Herein, we report the synthesis, characterization, and antimicrobial activity of silver nanoparticles with rhizome extract of Curcuma longa (AgNPs-RECL). Objective: To perform green synthesis of AgNPs-RECL, followed by their characterization via scanning electron microscopy (SEM), ultraviolet (UV)-visible spectroscopy, X-ray diffraction (XRD), Fourier transform-infrared spectroscopy (FT-IR), and high-performance liquid chromatography (HPLC). Further, antimicrobial activity of AgNPs-RECL was examined using disc diffusion test. Result: AgNPs-RECL showed antimicrobial activity towards two plant pathogenic bacteria Xanthomonas anoxopodis and Erwinia amylovora. Conclusion: It was concluded that AgNPs-RECL have the potential to inhibit plant pathogenic bacteria like Xanthomonas and Erwinia, which could be useful for nano drug delivery applications.
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